Read e-book online 2010-2011 Nelson's Pocket Book of Pediatric Antimicrobial PDF

By John S. Bradley MD, John D. Nelson MD Emeritus

ISBN-10: 1581104294

ISBN-13: 9781581104295

This best-selling and commonplace source on pediatric antimicrobial remedy presents fast entry to trustworthy, up to date suggestions for remedy of all infectious ailments in little ones. for every illness, the authors supply a observation to assist healthiness care prone choose the easiest of all antimicrobial offerings. Drug descriptions hide all antimicrobial brokers to be had this present day and contain entire information regarding dosing regimens. based on turning out to be issues approximately overuse of antibiotics, this system contains instructions on while to not prescribe antimicrobials. Key beneficial properties: designed if you look after childrens and are confronted with judgements on a daily basis; contains remedy of parasitic infections and tropical drugs; up-to-date anti-infective drug directory, whole with formulations and dosages; and balanced info on safeguard, efficacy, and tolerability with facts on bills and availability of drugs.

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Additional resources for 2010-2011 Nelson's Pocket Book of Pediatric Antimicrobial Therapy

Example text

BII) PO qd Adenitis, nontuberculous Excision usually curative (BII); azithromycin PO OR Antibiotic susceptibility patterns are quite variable; (atypical) mycobacterial8–11 clarithromycin PO x 6–12 wks (with or without cultures should guide therapy; medical therapy rifampin) if susceptible (BII) 60%–70% effective. Adenitis, acute bacterial1–7 Empiric IV therapy: May need surgical drainage (S aureus, including CA-MRSA, Standard: oxacillin 150 mg/kg/day IV div q6h OR For oral therapy for MSSA: cephalexin OR cloxacillin; for or group A streptococcus) cefazolin 100 mg/kg/day IV div q8h (AI) CA-MRSA: clindamycin, TMP/SMX, or linezolid CA-MRSA: clindamycin 30 mg/kg/day For group A strep: amoxicillin IV div q8h or vancomycin 40 mg/kg/day IV q8h (BII) Total IV plus PO therapy x 7–10 d Clinical Diagnosis NOTE: CA-MRSA (see Chapter 4 on CA-MRSA) is now prevalent in many areas of the world.

38,39 See Chapter 5. indd 35 – Other bacteria See Chapter 7 for preferred antibiotics. – Gonococcal arthritis or Ceftriaxone 50 mg/kg IV, IM q24h (BII); OR (if susceptible) PO cefixime 8 mg/kg/day (CII) as a single daily dose for tenosynovitis41,42 penicillin G 100,000 U/kg/day IV div q6h (AII); x 7 d penicillin-resistant strains. Quinolone resistance is increasing. – Infants (S aureus, including Empiric therapy: clindamycin (to cover CA-MRSA). For Oral therapy options: CA-MRSA; group A serious infections, ADD cefazolin to provide better For CA-MRSA: clindamycin OR linezolid40 streptococcus; Kingella MSSA coverage and add Kingella coverage For MSSA: cephalexin OR dicloxacillin kingae; in unimmunized or For CA-MRSA: clindamycin 30 mg/kg/day IV div q8h or For Kingella, most penicillins or cephalosporins (but not immune-compromised vancomycin 40 mg/kg/day IV q8h clindamycin) children: pneumococcus, For MSSA: oxacillin 150 mg/kg/day IV div q6h OR H influenzae type b) cefazolin 100 mg/kg/day IV div q8h Total therapy (IV plus PO) for 3 wks with normal ESR; – Children (S aureus, including For Kingella: cefazolin, ampicillin, or ceftriaxone 50 mg/ low-risk, non-hip arthritis may respond to a 10-day CA-MRSA; group A kg/day IV, IM q24h course.

100,111–114 40–60 mg/kg/day div q8h for S aureus (AIII) Consider H influenzae type b For suspect Mycoplasma/atypical pneumonia agents, pneumococcus: no need to add empiric vancomycin in the unimmunized child. particularly in school-aged children, ADD azithromycin for this reason (CIII) M pneumoniae may cause 10 mg/kg IV, PO x 1, then decrease dose to 5 mg/kg Oral therapy for pneumococcus and Haemophilus may lobar pneumonia. once daily for days 2–5 of treatment (AII) also be successful with: amox/clav, cefdinir, cefpodoxime Empiric oral outpatient therapy for less severe illness: or cefuroxime high dosage amoxicillin 80–100 mg/kg/day PO div q8h Levofloxacin is an alternative (BI)115 but due to cartilage (NOTq12h); for Mycoplasma, ADD a macrolide as toxicity concerns, should not be first-line therapy.

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2010-2011 Nelson's Pocket Book of Pediatric Antimicrobial Therapy by John S. Bradley MD, John D. Nelson MD Emeritus


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